TY - GEN A1 - Thiel, Sebastian T1 - Software framework for connecting several simulation-tools N2 - In Silico simulation of biological systems is an important sub area of computational biology (system biology), and becomes more and more an inherent part for research. Therefore, different kinds of software tools are required. At present, a multitude of tools for several areas exists, but the problem is that most of the tools are essentially application specific and cannot be combined. For instance, a software tool for the simulation of biochemical processes is not able to interact with tools for the morphology simulation and vice versa. In order to obtain realistic results with computer-aided simulations it is important to regard the biological system in its entirety. The objective is to develop a software framework, which provides an interface structure to combine existing simulation tools, and to offer an interaction between all affiliated systems. Consequently, it is possible to re-use existing models and simulation programs. Additionally, dependencies between those can be defined. The system is designed to interoperate as an extendable architecture for various tools. The thesis shows the usability and applicability of the software and discusses potential improvements. KW - Simulationswerkzeug KW - Systembiologie KW - Computational biology KW - Mediator framework Y1 - 2007 UR - https://kola.opus.hbz-nrw.de/frontdoor/index/index/docId/168 UR - https://nbn-resolving.org/urn:nbn:de:kola-1688 N1 - Titelblatt fehlt ER -