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- 2018 (1) (remove)
The present thesis describes the development of an OpenGL-based tool visualizing cavities of proteins, which can be observed during a static docking simulation. The goal is to achieve knowledge about interactions between proteins and ligands based on information about distances between them. At first chemical basics, which motivate the topic and are important for understanding the topic and the used algorithms, are presented. Furthermore existing software, which deals with similar issues, is described. Next the prerequisites for the development of the program are presented and the tool is described in detail. Concluding the tool is evaluated concerning performance and usage and a summarizing conclusion is given. The program turns out as a helpful tool for current research and a good base for further and deeper research projects.