UML models and OWL ontologies constitute modeling approaches with different strength and weaknesses that make them appropriate for use of specifying different aspects of software systems. In particular, OWL ontologies are well suited to specify classes using an expressive logical language with highly flexible, dynamic and polymorphic class membership, while UML diagrams are much more suitable for specifying not only static models including classes and associations, but also dynamic behavior. Though MOF based metamodels and UML profiles for OWL have been proposed in the past, an integrated use of both modeling approaches in a coherent framework has been lacking so far. We present such a framework, TwoUse, for developing integrated models, comprising the benefits of UML models and OWL ontologies