In order to enhance the company’s appeal for potential employees and improve the satisfaction of already salaried workers, it is necessary to offer a variety of work-life balance measures. But as their implementation causes time and financial costs, a prioritization of measures is needed. To express a recommendation for companies, this study is led by the questions if there are work-life balance measures which have more impact on employee satisfaction than others, how big the relative impact of work-life balance measures on job satisfaction in comparison to other work and private life variables is, if there is a relation between the effectiveness of measures and their use and if there is a difference between the measures which are most important from the employees’ perspective and the companies’ offers. These questions are formulated in eight research hypotheses which are examined in a quantitative research design with online survey data from 289 employees of fifteen different German companies. The formation of a hierarchy of the effectiveness of measures towards job satisfaction as well as the investigation of the relative impact in comparison to other variables is performed using a multiple regression analysis, whilst the differences between employees’ expectations and the availability of offers are examined with t-tests. Support in childcare, support in voluntary activities and teambuilding events have a significantly higher impact on job satisfaction than other work-life balance measures, and their potential use is higher than the actual use which leads to the conclusion that there is yet potential for companies to improve their employees’ satisfaction by implementing these measures. In addition, flexible work hours, flexible work locations and free time and overtime accounts are the most important measures from the employees’ point of view and already widely offered by the surveyed companies. In general, the overall use of the available measures and the quantity of offered measures are more important with regard to job satisfaction than the specific kind of measure. In addition, work-life balance measures are more important towards job satisfaction for younger people.