This dissertation deals with the opportunities and restrictions that parties face in an election campaign at the supranational level of the EU. Using communication science concepts of agenda-setting (focus: media) and agenda-building (focus: political parties), the first part of the study is based on the election campaign for the European Parliament (EP) in 2014. It analyses to what extent political parties put the EU on the agenda. Second, it is examined whether parties have used their structural advantage of being able to influence the media agenda at the supranational level during the election campaign in the context of the EP election campaign. Third, it is examined whether parties can gain an advantage for the visibility of their campaigns by rejecting EU integration and the associated conflictual communication. Fourth and final, it will be explored whether agenda-building can influence the rankings of specific policy issues on the media agenda in the European context. First, the analyses show that a European political focus of election campaign communication can no longer be found only on the part of the small (eurosceptic) parties. Second, parties have a good chance of being present in media coverage if the they pursue a European political focus in their campaign communication. Third, a negative tone in party communication turns out not to be decisive for the parties' visibility in the election campaign. Fourth, a clear positioning on political issues also prepares parties for restrictions of the further development of a European thematic agenda. After a discussion of these results, the paper concludes with an assessment of the analysis limitations and an outlook on further research approaches.