In this thesis the possibilities for real-time visualization of OpenVDB files are investigated. The basics of OpenVDB, its possibilities, as well as NanoVDB and its GPU port, were studied. A system was developed using PNanoVDB, the graphics API port of OpenVDB. Techniques were explored to improve and accelerate a single ray approach of ray tracing. To prove real-time capability, two single scattering approaches were also implemented. One of these was selected, further investigated and optimized to achieve interactive real-time rendering. It is important to give artists immediate feedback on their adjustments, as well as the possibility to change all parameters to ensure a user friendly creation process. In addition to the optical rendering, corresponding benchmarks were collected to compare different improvement approaches and to prove their relevance. Attention was paid to the rendering times and memory consumption on the GPU to ensure optimal use. A special focus, when rendering OpenVDB files, was put on the integrability and extensibility of the program to allow easy integration into an existing real-time renderer like U-Render.