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Institute
In Silico simulation of biological systems is an important sub area of computational biology (system biology), and becomes more and more an inherent part for research. Therefore, different kinds of software tools are required. At present, a multitude of tools for several areas exists, but the problem is that most of the tools are essentially application specific and cannot be combined. For instance, a software tool for the simulation of biochemical processes is not able to interact with tools for the morphology simulation and vice versa. In order to obtain realistic results with computer-aided simulations it is important to regard the biological system in its entirety. The objective is to develop a software framework, which provides an interface structure to combine existing simulation tools, and to offer an interaction between all affiliated systems. Consequently, it is possible to re-use existing models and simulation programs. Additionally, dependencies between those can be defined. The system is designed to interoperate as an extendable architecture for various tools. The thesis shows the usability and applicability of the software and discusses potential improvements.
Research has shown that people recognize personality, gender, inner states and many other items of information by simply observing human motion. Therefore the expressive human motion seems to be a valuable non-verbal communication channel. On the quest for more believable characters in virtual three dimensional simulations a great amount of visual realism has been achieved during the last decades. However, while interacting with synthetic characters in real-time simulations, often human users still sense an unnatural stiffness. This disturbance in believability is generally caused by a lack of human behavior simulation. Expressive motions, which convey personality and emotional states can be of great help to create more plausible and life-like characters. This thesis explores the feasibility of an automatic generation of emotionally expressive animations from given neutral character motions. Such research is required since common animation methods, such as manual modeling or motion capturing techniques, are too costly to create all possible variations of motions needed for interactive character behavior. To investigate how emotions influence human motion relevant literature from various research fields has been viewed and certain motion rules and features have been extracted. These movement domains were validated in a motion analysis and implemented in a system in an exemplary manner capable of automating the expression of angry, sad and happy states in a virtual character through its body language. Finally, the results were evaluated in user test.