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The cytological examination of bone marrow serves as clarification of variations in blood smears. It is also used for the clarification of anemia, as exclusion of bone marrow affection at lymphoma and at suspicion of leukemia. The morphological evaluation of hematopoietic cells is the basis for the creation of the diagnosis and for decision support for further diagnostics. Even for experienced hematologists the manual classification of hematopoietic cells is time-consuming, error-prone and subjective. For this reason new methods in the field of image processing and pattern recognition for the automatic classification including preprocessing steps are developed for a computer-assisted microscopy system. These methods are evaluated by means of a huge reference database. The proposed image analysis procedures comprise methods for the automated detection of smears, for the determination of relevant regions, for the localization and segmentation of single hematopoietic cells as well as for the feature extraction and classification task. These methods provide the basis for the first system for the automated, morphological analysis of bone marrow aspirates for leukemia diagnosis and are therefore a major contribution for a better and more efficient patient care in the future.
Texture-based text detection in digital images using wavelet features and support vector machines
(2010)
In this bachelor thesis a new texture-based approach for the detection of text in digital images is presented. The procedure can be essentially divided into two main tasks, in detection of text blocks and detection of individual words, whereby the individual words are extracted from the detected text blocks. Roughly, the developed method acts with multiple support vector machines, which classify possible text regions of an image into real text regions, using wavelet-based features. In the process the possible text regions are defifined by edge projections with diσerent orientations. The results of the approach are X/Y coordinates, width and height of rectangular regions of an image, which contains individual words. This knowledge can be further processed, for example by an optical character recognition software to get the important and useful text information.