Magnetic resonance (MR) tomography is an imaging method, that is used to expose the structure and function of tissues and organs in the human body for medical diagnosis. Diffusion weighted (DW) imaging is a specific MR imaging technique, which enables us to gain insight into the connectivity of white matter pathways noninvasively and in vivo. It allows for making predictions about the structure and integrity of those connections. In clinical routine this modality finds application in the planning phase of neurosurgical operations, such as in tumor resections. This is especially helpful if the lesion is deeply seated in a functionally important area, where the risk of damage is given. This work reviews the concepts of MR imaging and DW imaging. Generally, at the current resolution of diffusion weighted data, single white matter axons cannot be resolved. The captured signal rather describes whole fiber bundles. Beside this, it often appears that different complex fiber configurations occur in a single voxel, such as crossings, splittings and fannings. For this reason, the main goal is to assist tractography algorithms who are often confound in such complex regions. Tractography is a method which uses local information to reconstruct global connectivities, i.e. fiber tracts. In the course of this thesis, existing reconstruction methods such as diffusion tensor imaging (DTI) and q-ball imaging (QBI) are evaluated on synthetic generated data and real human brain data, whereas the amount of valuable information provided by the individual reconstruction mehods and their corresponding limitations are investigated. The output of QBI is the orientation distribution function (ODF), where the local maxima coincides with the underlying fiber architecture. We determine those local maxima. Furthermore, we propose a new voxel-based classification scheme conducted on diffusion tensor metrics. The main contribution of this work is the combination of voxel-based classification, local maxima from the ODF and global information from a voxel- neighborhood, which leads to the development of a global classifier. This classifier validates the detected ODF maxima and enhances them with neighborhood information. Hence, specific asymmetric fibrous architectures can be determined. The outcome of the global classifier are potential tracking directions. Subsequently, a fiber tractography algorithm is designed that integrates along the potential tracking directions and is able to reproduce splitting fiber tracts.