Model-Driven Engineering (MDE) aims to raise the level of abstraction in software system specifications and increase automation in software development. Modelware technological spaces contain the languages and tools for MDE that software developers take into consideration to model systems and domains. Ontoware technological spaces contain ontology languages and technologies to design, query, and reason on knowledge. With the advent of the Semantic Web, ontologies are now being used within the field of software development, as well. In this thesis, bridging technologies are developed to combine two technological spaces in general. Transformation bridges translate models between spaces, mapping bridges relate different models between two spaces, and, integration bridges merge spaces to new all-embracing technological spaces. API bridges establish interoperability between the tools used in the space. In particular, this thesis focuses on the combination of modelware and ontoware technological spaces. Subsequent to a sound comparison of languages and tools in both spaces, the integration bridge is used to build a common technological space, which allows for the hybrid use of languages and the interoperable use of tools. The new space allows for language and domain engineering. Ontology-based software languages may be designed in the new space where syntax and formal semantics are defined with the support of ontology languages, and the correctness of language models is ensured by the use of ontology reasoning technologies. These languages represent a core means for exploiting expressive ontology reasoning in the software modeling domain, while remaining flexible enough to accommodate varying needs of software modelers. Application domains are conceptually described by languages that allow for defining domain instances and types within one domain model. Integrated ontology languages may provide formal semantics for domain-specific languages and ontology technologies allow for reasoning over types and instances in domain models. A scenario in which configurations for network device families are modeled illustrates the approaches discussed in this thesis. Furthermore, the implementation of all bridging technologies for the combination of technological spaces and all tools for ontology-based language engineering and use is illustrated.